MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE

The present invention provides for compounds of Formula (I) (I) wherein R1 has any of the values defined in the specification, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the in...

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Bibliographische Detailangaben
Hauptverfasser:	HARDEE, David J, SCHMIDT, Robert G, SEARLE, Xenia B, HODGES, Timothy R, SCHRIMPF, Michael R
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides for compounds of Formula (I) (I) wherein R1 has any of the values defined in the specification, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention La présente invention concerne des composés de formule (I) dans laquelle R1 a l'une quelconque des valeurs définies dans la description, et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques les comprenant, et des méthodes de traitement de la fibrose kystique par l'administration d'un composé de l'invention