POLYPEPTIDE SPECIFIC FOR MUCIN 1 AND USE THEREOF

The present invention relates to a polypeptide binding to mucin 1, an isolated polynucleotide encoding same, a vector carrying the polynucleotide, and a cell including the vector. In addition, the present invention relates to a chimeric antigen receptor including the polypeptide binding to mucin 1,...

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Bibliographische Detailangaben
Hauptverfasser:	LEE, Ji Hyun, PARK, Areum, CHOE, Kyuhong, JUNG, Saem, CHOI, Jungwon, SONG, Eu Rim, CHOI, Yoon Aa, YI, Dae Gwan, LEE, Hae Youn, JANG, Sung Woong, YI, Hyoju, NA, Kyubong, PARK, Min Jeong, JEUN, Eun Ji, YANG, Hee Jung
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a polypeptide binding to mucin 1, an isolated polynucleotide encoding same, a vector carrying the polynucleotide, and a cell including the vector. In addition, the present invention relates to a chimeric antigen receptor including the polypeptide binding to mucin 1, an isolated polynucleotide encoding the chimeric antigen receptor, a vector carrying the polynucleotide, an immune cell expressing the chimeric antigen receptor, a composition comprising same for treatment of cancer, and a method for treatment of cancer. La présente invention concerne un polypeptide se liant à la mucine 1, un polynucléotide isolé le codant, un vecteur portant le polynucléotide, et une cellule comprenant le vecteur. De plus, la présente invention concerne un récepteur d'antigène chimérique comprenant le polypeptide se liant à la mucine 1, un polynucléotide isolé codant le récepteur d'antigène chimérique, un vecteur portant le polynucléotide, une cellule immunitaire exprimant le récepteur d'antigène chimérique une composition le comprenant pour le traitement du cancer, et un procédé de traitement du cancer. 뮤신1(Mucin1)에 결합하는 폴리펩티드, 이를 코딩하는 단리된 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 벡터, 및 상기 벡터를 포함하는 세포에 관한 것이다. 또한, 뮤신1에 결합하는 폴리펩티드를 포함하는 키메라 항원 수용체, 상기 키메라 항원 수용체를 코딩하는 단리된 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 벡터, 상기 키메라 항원 수용체를 발현하는 면역 세포, 및 이들을 포함하는 암 치료용 조성물 및 치료 방법에 관한 것이다.