CHIRAL INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND SHIP ANTI-FOULING USE THEREOF

The present invention relates to a chiral 3-cyclic indole compound represented by formula (I), which uses 3-methylhydroxyindole as a raw material, a chiral intermediate is obtained under the action of a chiral catalyst, and then a chiral compound having anti-fouling potential is obtained by passing...

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Hauptverfasser: ZHENG, Shaojun, WU, Wenbin, TAN, Yi, FANG, Yue, ZHU, Rui, LIN, Chuansong, DAI, Huihui
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:The present invention relates to a chiral 3-cyclic indole compound represented by formula (I), which uses 3-methylhydroxyindole as a raw material, a chiral intermediate is obtained under the action of a chiral catalyst, and then a chiral compound having anti-fouling potential is obtained by passing through four reaction steps, thus improving the atom utilization rate. The process is simple, the product has high purity, the present invention has very high bactericidal activity against Escherichia coli and Staphylococcus aureus, and has excellent application prospects in ship anti-fouling. La présente invention concerne un composé d'indole 3-cyclique chiral représenté par la formule (I), qui utilise du 3-méthylhydroxyindole en tant que matière première, un intermédiaire chiral est obtenu sous l'action d'un catalyseur chiral, puis un composé chiral ayant un potentiel anti-encrassement est obtenu en passant par quatre étapes de réaction, améliorant ainsi le taux d'utilisation d'atomes. Le procédé est simple, le p