BIFIDOBACTERIUM BREVE STRAIN CAPABLE OF PREVENTING AND ALLEVIATING PSORIASIS, AND APPLICATION THEREOF

Provided is a Bifidobacterium breve strain capable of preventing and alleviating psoriasis, and an application thereof, belonging to the technical field of micro-organisms and the technical field of medicines. Provided are new uses of Bifidobacterium breve CCFM1078 in suppressing IL-23/Th17 axis-rel...

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Hauptverfasser:	ZHANG, Hao, LU, Wenwei, CUI, Shumao, DENG, Yadan, MAO, Bingyong, WANG, Hongchao, YANG, Bo, ZHAO, Jianxin, ZHAI, Qixiao, CHEN, Wei
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MAKING THEREOF MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MILK OR CHEESE SUBSTITUTES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided is a Bifidobacterium breve strain capable of preventing and alleviating psoriasis, and an application thereof, belonging to the technical field of micro-organisms and the technical field of medicines. Provided are new uses of Bifidobacterium breve CCFM1078 in suppressing IL-23/Th17 axis-related inflammatory factor release and in the relief of psoriasis. Bifidobacterium breve CCFM1078 can alleviate the skin lesions of psoriasis-like mice and inhibit the thickening of the epidermal skin layer, and decrease the levels of IL-23, IL-22, and IL-17 in the skin by 20.3%, 22.0%, and 18.3%, respectively; in the preparation of products for the prevention and/or treatment of psoriasis (e.g. food products, drugs, health foods, etc.) the invention has enormous prospects for application. L'invention concerne une souche de Bifidobacterium breve capable de prévenir et d'atténuer le psoriasis, et une application de celle-ci, appartenant au domaine technique des micro-organismes et au domaine technique des médicaments.