BICYCLIC PYRAZOLE BRUTON'S TYROSINE KINASE INHIBITORS

The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL. La présente invention concerne des composés de formule (...

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Bibliographische Detailangaben
Hauptverfasser:	ZABLOCKI, Jeffery A, DUBOVYK, Igor, OKANO, Akinori, DOMBROWSKI, Amanda W, NOEY, Elizabeth L, KHRAKOVSKY, Dimitri, DEANDA, JR, GRESZLER, Stephen N, DEGOEY, David A, SOUERS, Andrew J, WANG, Longcheng, NEWTON, James N, WILSON, Noel S, SIPPY, Kevin B, LEE, Chih-Hung
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL. La présente invention concerne des composés de formule (I) (I); A, R1, R2, R4, W, m et n ayant l'une quelconque des valeurs définies dans la description, et des sels pharmaceutiquement acceptables de ceux-ci, qui sont utiles en tant qu'agents dans le traitement de la LLC et/ou du SLL.