N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS

The invention relates to inhibitors of anaphase promoting complex/cyclosome (APC/C) function of formula (I), wherein the meaning for R1 and R2 is as disclosed in the description. These compounds are useful in the treatment of cancer, particularly, in the treatment of breast cancer. L'invention...

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Bibliographische Detailangaben
Hauptverfasser:	BOLANOS-GARCÍA, Víctor M, CURTIS, Natalie Laura, BASTIDA CODINA, Agatha, BENITO ARENAS, Raúl
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to inhibitors of anaphase promoting complex/cyclosome (APC/C) function of formula (I), wherein the meaning for R1 and R2 is as disclosed in the description. These compounds are useful in the treatment of cancer, particularly, in the treatment of breast cancer. L'invention concerne des inhibiteurs de la fonction du complexe de promotion de l'anaphase/cyclosome (APC/C) représentés par la formule (I), la signification de R1 et R2 étant telle que divulguée dans la description. Ces composés sont utiles dans le traitement du cancer, en particulier, dans le traitement du cancer du sein.