LACTOBACILLUS GASSERI AND USE THEREOF FOR RELIEVING AND TREATING HYPERURICEMIA

Provided are Lactobacillus gasseri CCFM1133 and a use thereof for relieving and treating hyperuricemia. Lactobacillus gasseri can reduce serum uric acid levels as well as serum and liver xanthine oxidase (XOD) activity in hyperuricemic mice, and reduce the occurrence of hyperuricemia and gout; furth...

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Hauptverfasser: NI, Caixin, WANG, Linlin, ZHANG, Hao, WANG, Gang, ZHAO, Jianxin, CHEN, Wei
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:Provided are Lactobacillus gasseri CCFM1133 and a use thereof for relieving and treating hyperuricemia. Lactobacillus gasseri can reduce serum uric acid levels as well as serum and liver xanthine oxidase (XOD) activity in hyperuricemic mice, and reduce the occurrence of hyperuricemia and gout; furthermore, Lactobacillus gasseri is capable of regulating the blood sugar and serum triglyceride (TG) levels of hyperuricemia patients, increasing the activity of liver catalase (CAT) and glutathione peroxidase (GSH-Px), increasing the expression of ileum ABCG2, promoting the excretion of intestinal uric acid, and increasing the intestinal short-chain fatty acids levels, which promote health. The invention can be used for preparing food, functional food or medicine. La présente invention concerne Lactobacillus gasseri CCFM1133 et son utilisation pour soulager et traiter l'hyperuricémie. Lactobacillus gasseri peut réduire les niveaux d'acide urique sérique ainsi que l'activité de la xanthine oxydase (XOD) sérique et hé