CANCER TREATMENT USING BOSENTAN IN COMBINATION WITH A CHECKPOINT INHIBITOR

The present invention is directed to a combination treatment using bosentan and a checkpoint inhibitor that is effective in treating cancer or inhibiting the proliferation of tumor cells in a subject and/or that can initiate, enhance or prolong the immune response to tumor cells. La présente inventi...

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Bibliographische Detailangaben
Hauptverfasser: STYLIANOPOULOS, Triantafyllos, PANAGI, Myrofora, MARTIN, John D, MPEKRIS, Fotios, STYLIANOU, Andreas, VOUTOURI, Chrysovalantis
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention is directed to a combination treatment using bosentan and a checkpoint inhibitor that is effective in treating cancer or inhibiting the proliferation of tumor cells in a subject and/or that can initiate, enhance or prolong the immune response to tumor cells. La présente invention concerne un traitement combiné utilisant du bosentan et un inhibiteur de point de contrôle qui est efficace dans le traitement du cancer ou l'inhibition de la prolifération de cellules tumorales chez un sujet et/ou qui peut initier, améliorer ou prolonger la réponse immunitaire à des cellules tumorales.