METHOD FOR AMMOXIMATION OF MACROCYCLOALKANONE

The present invention provides a method for ammoximation of macrocycloalkanone, comprising the following steps: adding hydrogen peroxide, ammonia water, a hydroxylamine stabilizer, an oximation catalyst, a solvent, and a macrocycloalkanone into an oximation reactor for reaction to obtain a reaction solution, cooling the reaction solution from a reaction temperature to 0-40℃ gradually, and carrying out cooling crystallization by means of a crystallization separator to obtain cycloalkanone oxime. According to the method for oximation of macrocycloalkanone provided by the present invention, the utilization rate of hydrogen peroxide solution is 98.3%-99.9%, the molar yield of the macrocycloalkanone oxime corresponding to macrocycloalkanone is 99.2%-99.9%, the macrocycloalkanone oxime having a content of 99.9% is obtained by means of cooling crystallization separation, and a mother solution is distilled off by a water removal column to achieve solvent system cyclic utilization. La présente invention concerne un pr