HUMANIZED ANTIBODY AGAINST NOVEL CORONAVIRUS-SPECIFIC ANTIGENIC PEPTIDES, PREPARATION METHOD AND USE

The present disclosure relates to a humanized antibody against novel coronavirus-specific antigenic peptides, a preparation method and the use. In particular, the present disclosure relates to an anti-SARS-CoV-2 antibody or an antigen-binding fragment thereof, and the use thereof in the diagnosis of...

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Hauptverfasser: GAO, Meiling, LI, Lili, DUAN, Jing, WAN, Dingyi, WANG, Yanan, YANG, Heng
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:The present disclosure relates to a humanized antibody against novel coronavirus-specific antigenic peptides, a preparation method and the use. In particular, the present disclosure relates to an anti-SARS-CoV-2 antibody or an antigen-binding fragment thereof, and the use thereof in the diagnosis of diseases, the preparation of a COVID-19 vaccine, and the preparation of a medicament for preventing and treating COVID-19. The anti-SARS-CoV-2 antibody or the antigen-binding fragment thereof of the present disclosure can bind to the RBD domain of the novel coronavirus and block the invasion of cells by the virus, having important clinical significance for the prevention, treatment or detection of the novel coronavirus. La présente divulgation concerne un anticorps humanisé dirigé contre de nouveaux peptides antigéniques spécifiques du coronavirus, un procédé de préparation et une utilisation. En particulier, la présente divulgation concerne un anticorps anti-SARS-CoV-2 ou un fragment de liaison à l'antigène de ce