IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS

The present invention relates to imidazo[4,5-c]quinoline compounds and to their use in the inhibition, regulation and/or modulation of signal transduction by ATM kinase and, in particular, for the treatment of ATM mediated diseases, especially cancer. La présente invention concerne des composés imid...

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Bibliographische Detailangaben
Hauptverfasser:	DIMITROV, Teodor, LAUFER, Stefan, FORSTER, Michael, MOSCHOPOULOU, Athina, ZENDER, Lars
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to imidazo[4,5-c]quinoline compounds and to their use in the inhibition, regulation and/or modulation of signal transduction by ATM kinase and, in particular, for the treatment of ATM mediated diseases, especially cancer. La présente invention concerne des composés imidazo[4,5-c]quinoléine et leur utilisation pour inhiber, réguler et/ou moduler la transduction de signal par la kinase ATM et, en particulier, pour le traitement de maladies à médiation par ATM, en particulier le cancer.