METHOD FOR DETECTING RNA STRUCTURE AT WHOLE TRANSCRIPTOME LEVEL AND USE THEREOF

Provided in the present invention are a method for detecting an RNA structure and the use thereof. According to the present invention, the step of removing the background of reverse transcription termination signals is included in the method for detecting an RNA structure, and false positive signals...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG, Qiangfeng, PIAO, Meiling
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided in the present invention are a method for detecting an RNA structure and the use thereof. According to the present invention, the step of removing the background of reverse transcription termination signals is included in the method for detecting an RNA structure, and false positive signals in a structural score calculation are reduced, and therefore the accuracy of the detection method is improved. La présente invention concerne un procédé de détection de la structure d'un ARN et son utilisation. Selon la présente invention, l'étape de suppression du fond des signaux de terminaison de transcription inverse est incluse dans le procédé de détection d'une structure d'ARN, et les signaux faux positifs dans un calcul de score structurel sont réduits, et donc la précision du procédé de détection est améliorée. 本发明提供了一种RNA结构检测方法及其应用。本发明通过在RNA结构检测方法中包括去除背景逆转录终止信号的步骤，降低了结构分数计算中的假阳性信号，从而提高检测方法的准确性。