A SOLID DISPERSION OF PONATINIB HYDROCHLORIDE AND PROCESS OF PREPARATION THEREOF

A SOLID DISPERSION OF PONATINIB HYDROCHLORIDE AND PROCESS OF PREPARATION THEREOF

The present subject matter relates to a solid oral pharmaceutical composition comprising ponatinib or a pharmaceutically acceptable salt thereof and at least one pharmaceutical acceptable excipient. The present subject matter also relates to pharmaceutical compositions comprising a solid dispersion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KOTHADIYA, Mahesh, PANCHAL, Chirag, HAZRA, Debasis, SAHOO, Ashok Kumar, KADAM, Abhijit, DABRE, Rahul, TAMBOLI, Parimal, SAHOO, Barada Prasanna, VITTAL, T.V.S.K
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present subject matter relates to a solid oral pharmaceutical composition comprising ponatinib or a pharmaceutically acceptable salt thereof and at least one pharmaceutical acceptable excipient. The present subject matter also relates to pharmaceutical compositions comprising a solid dispersion of ponatinib or a pharmaceutically acceptable salt thereof and at least one pharmaceutical acceptable excipient. Furthermore, it also relates to process of preparation of such compositions, and uses thereof. La présente invention concerne une composition pharmaceutique orale solide comprenant du ponatinib ou un sel pharmaceutiquement acceptable de celui-ci et au moins un excipient pharmaceutiquement acceptable. La présente invention concerne également des compositions pharmaceutiques comprenant une dispersion solide de ponatinib ou un sel pharmaceutiquement acceptable de celui-ci et au moins un excipient pharmaceutiquement acceptable. De plus, l'invention concerne également un procédé de préparation de telles compositions, et leurs utilisations.