SOLVATE FORMS OF A PAN-JAK INHIBITOR

The present invention provides crystalline solvate and solvate/hydrate forms of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile, and methods of making and using the same. La présente invention concerne des formes cristal...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	EDWARDS, Richard, WOMBWELL, Claire, GIELEN, Bjorn, COLLAS, Alain, GEERTMAN, Robert Michael, ASHURST, Kate, DE DOBBELAERE, Christopher
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention provides crystalline solvate and solvate/hydrate forms of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile, and methods of making and using the same. La présente invention concerne des formes cristallines solvatées et des formes solvatées/hydratées de 3-((1R,3s,5S)-3-((7-((5-méthyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile et des procédés de fabrication et d'utilisation de ceux-ci.