MODIFICATION OF A NANOPORE FORMING PROTEIN OLIGOMER

Provided herein is a method of chemically modifying a polypeptide or polynucleotide monomer. The monomer may be a monomer of a protein pore such as a monomeric or oligomeric protein pore. Also disclosed are related monomers and oligomers and methods of using the disclosed pores in characterising ana...

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Bibliographische Detailangaben
Hauptverfasser:	MALAVIARACHCHIGE RABEL, Ranga Prabhath, BLACKWELL, Kimberley Emma, KILGOUR, John Joseph, SINGH, Pratik Raj, JAYASINGHE, Lakmal Nishantha, WALLACE, Elizabeth Jayne
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEASURING METALLURGY NANOTECHNOLOGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICS SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	Provided herein is a method of chemically modifying a polypeptide or polynucleotide monomer. The monomer may be a monomer of a protein pore such as a monomeric or oligomeric protein pore. Also disclosed are related monomers and oligomers and methods of using the disclosed pores in characterising analytes. L'invention concerne un procédé de modification chimique d'un polypeptide ou d'un monomère polynucléotidique. Le monomère peut être un monomère d'un pore protéique tel qu'un pore protéique monomère ou oligomère. L'invention concerne également des monomères et des oligomères associés et des procédés d'utilisation des pores décrits dans la caractérisation d'analytes.