HEMOSTATIC FORMULATIONS AND USES THEREOF

Disclosed herein are formulations comprised of concentrated Factor V, vitamin Independent clotting protein and a stabilizer, wherein the stabilizer is at a concentration at which the Factor V or the vitamin K-dependent clotting protein are in the zymogen form. Also disclosed herein are processes for...

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Bibliographische Detailangaben
Hauptverfasser:	YUNUSOV, Marina, MINTZ, Roni, NUR, Israel, VISNOVEZKY, Damian, LESHETS, Michael
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed herein are formulations comprised of concentrated Factor V, vitamin Independent clotting protein and a stabilizer, wherein the stabilizer is at a concentration at which the Factor V or the vitamin K-dependent clotting protein are in the zymogen form. Also disclosed herein are processes for the preparation of the formulations. L'invention concerne des formulations constituées d'un facteur V concentré, d'une protéine de coagulation indépendante de la vitamine et un stabilisant, le stabilisant étant à une concentration à laquelle le facteur V ou la protéine de coagulation dépendante de la vitamine K se trouvent sous forme zymogène. L'invention concerne également des procédés de préparation des formulations.