SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS

SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS

This disclosure is drawn to substituted pyridine compounds and compositions, and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing neurological diseases. La présente divulgation concerne des composés de pyridine substitués et des compositions de ceux-ci, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SAMBASHIVAN, Shilpa, ZHU, Liusheng, BROWN, Sean Pomeroy, GARLAND, Keira, TEGLEY, Christopher Michael
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This disclosure is drawn to substituted pyridine compounds and compositions, and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing neurological diseases. La présente divulgation concerne des composés de pyridine substitués et des compositions de ceux-ci, ainsi que des procédés associés, utiles pour inhiber l'activité de SARM1 et/ou pour traiter ou prévenir des maladies neurologiques.