BIOMARKERS AND USES THEREOF IN THE TREATMENT OF CHRONIC HBV INFECTION

Immunogenetic biomarkers of viral control of chronic hepatitis B (CHB) infection that are indicative of relapse after a viral suppression treatment, such as a NUC treatment, in CHB infected subject are described. Also described are methods and compositions of using the immunogenetic biomarkers in pr...

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Hauptverfasser:	TUEFFERD, Marianne Isabelle, CRABBE, Marjolein, AERSSENS, Jeroen Marcel Maria Roger, BOLLEKENS, Jacques Armand Henri, DI CARA, Alessandro
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Immunogenetic biomarkers of viral control of chronic hepatitis B (CHB) infection that are indicative of relapse after a viral suppression treatment, such as a NUC treatment, in CHB infected subject are described. Also described are methods and compositions of using the immunogenetic biomarkers in predicting the relapse in the viral suppression treatment of CHB infection. L'invention concerne des biomarqueurs immunogénétiques de la régulation virale d'une infection à hépatite B chronique (HBC) qui indiquent une rechute après un traitement de suppression virale, tel qu'un traitement par NUC, chez un sujet infecté par l'HBC. L'invention concerne également des compositions et des méthodes d'utilisation de ces biomarqueurs immunogénétiques pour prédire la rechute dans le traitement de suppression virale d'une infection à HBC.