DRUG BALLOON AND PREPARATION METHOD THEREFOR

The present invention relates to a drug balloon and a preparation method therefor. The drug balloon comprises a balloon body and a coating provided on the surface of the balloon body; the coating sequentially comprises a bottom layer, a drug-carrying layer, and a functional layer from inside to outs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: NAN, Wenbin, ZHU, Qing, ZHU, Yimen, GUO, Fang
Format: Patent
Sprache:chi ; eng ; fre
Schlagworte:
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Beschreibung
Zusammenfassung:The present invention relates to a drug balloon and a preparation method therefor. The drug balloon comprises a balloon body and a coating provided on the surface of the balloon body; the coating sequentially comprises a bottom layer, a drug-carrying layer, and a functional layer from inside to outside; the bottom layer comprises a hydrophilic material and/or a lipophilic material; the drug-carrying layer comprises a drug and a carrier; the functional layer comprises a drug and a functional material; and the functional material comprises at least one of a drug receptor protein inhibitor, a drug metabolism isoenzyme inducer, and a drug metabolism isoenzyme inhibitor. Thus, by means of the bottom layer, the adhesion of the drug to the surface of the balloon can be reduced, and residues of the drug on the surface of the balloon can be reduced; moreover, by means of the functional layer, the loss of the drug during a delivery process can be reduced, and the speed of drug metabolism can be adjusted. La présente in