INHIBITOR FOR AUTOPHAGY AND APOPTOSIS OF RETINAL PIGMENT EPITHELIUM (RPE), AND USE THEREOF

An inhibitor for the autophagy and apoptosis of retinal pigment epithelium (RPE), and the use thereof, which relate to the technical field of biomedicine. The inhibitor for the autophagy and apoptosis of retinal pigment epithelium (RPE) comprises a Met antagonist of a tumor necrosis factor superfamily receptor FAS. Upon verification, the tumor necrosis factor superfamily receptor FAS can be used as a receptor of GMFB to activate a downstream autophagy and apoptotic pathway, whereas the Met antagonist thereof can inhibit the activation of the FAS and downstream relevant pathways thereof, and reduce cell apoptosis and autophagy responses, thereby delaying the pathogenesis of diabetic retinopathy. The inhibitor can be used for preparing a drug for delaying and/or treating diabetic retinopathy at the early stage of the pathogenesis thereof. Un inhibiteur pour l'autophagie et l'apoptose de l'épithélium pigmentaire rétinien (RPE), et son utilisation, qui concerne le domaine technique de la biomédecine. L'inhibiteur