CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS

The present invention relates to compounds for their use in the reactivation of butyrylcholinesterase. Such compounds are useful in the treatment or prevention of the intoxication with at least one organophosphorus nerve agent. The invention also relates to pharmaceutical compositions and kits compr...

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Bibliographische Detailangaben
Hauptverfasser:	RENARD, Pierre-Yves, NACHON, Florian, DUBOIS-GEOFFROY, Pierre, PROBST, Nicolas, DIAS, José, BRAÏKI, Anissa, JEAN, Ludovic
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds for their use in the reactivation of butyrylcholinesterase. Such compounds are useful in the treatment or prevention of the intoxication with at least one organophosphorus nerve agent. The invention also relates to pharmaceutical compositions and kits comprising said compounds, and compounds per se. La présente invention concerne des composés destinés à être utilisés dans la réactivation de la butyrylcholinestérase. De tels composés sont utiles dans le traitement ou la prévention de l'intoxication par au moins un agent neurotoxique organophosphoré. L'invention concerne également des compositions pharmaceutiques et des kits comprenant lesdits composés, ainsi que des composés per se.