BIFUNCTIONAL MOLECULES TARGETING PD-L1 AND TGF-BETA
Provided are anti-PD-L1 antibodies with superior activities in blocking the PD-1 and PD-L1 interactions. Also provided are multifunctional molecules that include the anti-PD-L1 antibodies or fragments thereof fused to an extracellular domain of human TGF-beta receptor type-2. L'invention concer...
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| creator | GONG, Wenci TOU, Yiwei |
| description | Provided are anti-PD-L1 antibodies with superior activities in blocking the PD-1 and PD-L1 interactions. Also provided are multifunctional molecules that include the anti-PD-L1 antibodies or fragments thereof fused to an extracellular domain of human TGF-beta receptor type-2.
L'invention concerne des anticorps anti-PD-L1 présentant des activités supérieures en termes de blocage des interactions PD-1 et PD-L1. L'invention concerne également des molécules multifonctionnelles qui comprennent les anticorps anti-PD-L1 ou des fragments de ceux-ci fusionnés à un domaine extracellulaire du récepteur de TGF-bêta humain de type 2. |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | BIFUNCTIONAL MOLECULES TARGETING PD-L1 AND TGF-BETA |
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