CURCUMIN DIHYDROPYRIDONE DERIVATIVES WITH ANTI-CANCER ACTIVITY

The present invention includes DHPDO curcumin derivatives (6) having the following general structure: These DHPDO curcumin derivatives have pronounced anti-cancer activity with lower toxicity on normal cells. Specifically, these compounds can be used in the treatment of breast cancer and colorectal...

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description The present invention includes DHPDO curcumin derivatives (6) having the following general structure: These DHPDO curcumin derivatives have pronounced anti-cancer activity with lower toxicity on normal cells. Specifically, these compounds can be used in the treatment of breast cancer and colorectal cancer. La présente invention concerne des dérivés de curcumine DHPDO (6) ayant la structure générale suivante : 6 Ces dérivés de curcumine DHPDO présentent une activité anticancéreuse prononcée avec une faible toxicité sur des cellules normales. En particulier, ces composés peuvent être utilisés dans le traitement du cancer du sein et du cancer colorectal.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CURCUMIN DIHYDROPYRIDONE DERIVATIVES WITH ANTI-CANCER ACTIVITY
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