METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES

Provided herein are methods of treating B-cell proliferative disorders (such as Follicular Lymphoma and diffuse large B cell lymphoma) using immunoconjugates comprising anti-CD79b antibodies in combination with a Bcl-2 inhibitor (such as venetoclax) and an anti-CD20 antibody (such as obinutuzumab or...

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Hauptverfasser: MUSICK, Lisa, HIRATA, Jamie Harue
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided herein are methods of treating B-cell proliferative disorders (such as Follicular Lymphoma and diffuse large B cell lymphoma) using immunoconjugates comprising anti-CD79b antibodies in combination with a Bcl-2 inhibitor (such as venetoclax) and an anti-CD20 antibody (such as obinutuzumab or rituximab). L'invention concerne des méthodes de traitement de troubles prolifératifs à cellules B (tels que le lymphome folliculaire et le lymphome diffus à grandes cellules B) à l'aide d'immunoconjugués comprenant des anticorps anti-CD79b en combinaison avec un inhibiteur de Bcl-2 (tel que le vénétoclax) et un anticorps anti-CD20 (tel que l'obinutuzumab ou le rituximab).