CRYSTAL FORM OF THIOFURAN PYRIDAZINE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

The present invention provides a crystal form of a thiofuran pyridazine compound, a preparation method therefor and an application thereof. The crystal form of the thiofuran pyridazine compound is (S)-2-(4-fluorophenyl)-4-(piperidine-3-aminomethyl)thieno[2,3-d]pyridazine-7-carboxamide hydrochloride...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG, Dingfeng, LV, Yonghui, WU, Guofeng, SHEN, Dadong, CAO, Ruiwei
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a crystal form of a thiofuran pyridazine compound, a preparation method therefor and an application thereof. The crystal form of the thiofuran pyridazine compound is (S)-2-(4-fluorophenyl)-4-(piperidine-3-aminomethyl)thieno[2,3-d]pyridazine-7-carboxamide hydrochloride of formula (I). The crystal form of the thiofuran pyridazine compound in the present invention has higher stability, is stored especially in high humidity conditions, and thus is suitable for preparing various forms of drugs. La présente invention concerne une forme cristalline d'un composé thiofurane pyridazine, son procédé de préparation et son utilisation. La forme cristalline du composé de thiofurane pyridazine est le chlorhydrate de (S)-2-(4-fluorophényl)-4-(pipéridine-3-aminométhyl)thiéno[2,3-d]pyridazine-7-carboxamide de formule (I). La forme cristalline du composé de thiofurane pyridazine selon la présente invention a une stabilité supérieure, est stockée en particulier dans des conditions d'humidité élevée