FGFR3-TARGETED RADIOIMMUNOCONJUGATES AND USES THEREOF

Radioimmunoconjugates including a chelating moiety or a metal complex thereof, a linker, and an FGFR3 targeting moiety. Pharmaceutical compositions of such radioimmunoconjugates and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention concerne d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GRINSHTEIN, Natalie, BURAK, Eric Steven, SCHWABISH, Marc
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Radioimmunoconjugates including a chelating moiety or a metal complex thereof, a linker, and an FGFR3 targeting moiety. Pharmaceutical compositions of such radioimmunoconjugates and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention concerne des radioimmunoconjugués comprenant une fraction chélatante ou un complexe métallique associé, un lieur et une fraction de ciblage de FGFR3. L'invention concerne également des compositions pharmaceutiques de tels radioimmunoconjugués et des méthodes de traitement d'états, par exemple, le cancer, à l'aide de ces compositions pharmaceutiques.