STAT INHIBITORY COMPOUNDS AND COMPOSITIONS

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for e...

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Bibliographische Detailangaben
Hauptverfasser:	FLECK, Roman, KRASKOUSKAYA, Dziyana, JOHN, Alford Antoine, PROUDFOOT, John, PALERM, Angel Sampedro, DARWISH, Alla, OMEARA, Jeff, GNANASEKARAN, Krishna Kumar, GUNNING, Patrick Thomas, ALI, Ahmed Magdy Ahmed Mohamed
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer. L'invention concerne des composés et des compositions pharmaceutiques comprenant lesdits composés qui sont utiles pour l'inhibition du signal transducteur et activateur de la transcription 5a et 5b (STAT5). En outre, les composés et compositions de l'invention sont utiles pour le traitement du cancer, tel que, par exemple, le cancer du sein et le cancer du pancréas.