METHODS FOR TREATMENT OF CANCER WITH AN ANTI-TIGIT ANTAGONIST ANTIBODY

The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a me...

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Bibliographische Detailangaben
Hauptverfasser:	CHA, Edward Namserk, WANG, Yulei, ZHANG, Xiaosong, KOMATSUBARA, Kimberly Mayumi, HOANG, Tien, PHAM, Thinh Quang, MENG, Raymond D, LEE, Anthony Jongha, BENNETT, Elizabeth Alexandra, LIN-LIU, Yvonne Gail, MATHENY, Christina Jeanne, GITLITZ, Barbara Jennifer, ROONEY, Isabelle Anne, CHAN, Hui Min Phyllis, CHUI, Stephen, YAN, Yibing, WANG, Lijia, BARAK, Hila, NGUYEN DUC, Anh, BALLINGER, Marcus Dale, ZHANG, Aijing, LAI, Catherine, LAU, Janet, TROUTMAN, Sarah Marie, PATEL, Jilpa Bhupendra, WILLIAMS, Patrick Georges Robert, CASTRO, Marcela Lucia, WU, Benjamin, LI, Shi, MENDUS, Diana, STEVENS, Heather Blythe, COTTER, Christopher Roland, DEGAONKAR, Viraj Vinay
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy. La présente invention concerne des méthodes, des utilisations et des compositions pour le traitement du cancer (par exemple, un cancer du poumon; un cancer du col de l'utérus; un cancer du sein; le cancer de la tête et du cou; un cancer du foie ; un cancer de la vessie ; un cancer gastrique ; un cancer de l'œsophage ; un cancer du pancréas ; un cancer du rein ou rénal ; un mélanome ; un cancer de l'ovaire ; ou un cancer colorectal). Plus spécifiquement, l'invention concerne le traitement de patients atteints d'un cancer avec un anticorps antagoniste anti-TIGIT, comprenant le traitement avec un anticorps antagoniste anti-TIGIT dans une polythérapie.