COMPOSITION FOR INHIBITING GROWTH OF CANCER STEM CELLS, CONTAINING WDR34 INHIBITOR, AND USE THEREOF

The present invention relates to a composition for inhibiting the growth of cancer stem cells, and a use thereof. A WDR34 inhibitor of the present invention inhibits the conversion of cancer cells into cancer stem cells and exhibits activity of inhibiting self-renewal, invasion, and migration of can...

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Bibliographische Detailangaben
Hauptverfasser:	KAHM, Yeon Jee, KIM, Rae Kwon, KIM, In Gyu
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a composition for inhibiting the growth of cancer stem cells, and a use thereof. A WDR34 inhibitor of the present invention inhibits the conversion of cancer cells into cancer stem cells and exhibits activity of inhibiting self-renewal, invasion, and migration of cancer stem cells, and thus can be effectively used as a cancer cell growth or metastasis inhibitor or a cancer stem cell growth inhibitor. La présente invention concerne une composition pour inhiber la croissance de cellules souches cancéreuses et une utilisation correspondante. Un inhibiteur de WDR34 de la présente invention inhibe la conversion de cellules cancéreuses en cellules souches cancéreuses et présente une activité d'inhibition de l'autorenouvellement, de l'invasion et de la migration de cellules souches cancéreuses et peut ainsi être efficacement utilisé en tant qu'inhibiteur de croissance ou de métastase de cellules cancéreuses ou inhibiteur de croissance de cellules souches cancéreuses. 본 발명은 암줄기세포 성장 억제용 조성물 및 이의 용도에 관한 것으로, 본 발명의 WDR34 억제제는 암세포의 암줄기세포화를 억제하고, 암줄기세포의 자가재생, 침윤 및 이동을 저해하는 활성을 나타내어 암세포 성장 또는 전이 억제제, 또는 암줄기세포 성장 억제제로써 유용하게 활용할 수 있다.