CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS
Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target...
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creator | BERLIN, Shai ZOABI, Shaden CARMI, Ido |
description | Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.
L'invention concerne des formes modifiées de peptides de conantokine, comprenant fes peptides Con-P modifiés, des acides nucléiques codant pour ceux-ci et des compositions de ceux-ci. L'invention concerne en outre des molécules d'acides nucléiques codant pour des polypeptides de conantokine modifiés chimériques devant être exprimés dans ou sur une membrane d'une cellule cible, des compositions les comprenant et leurs utilisations pour traiter diverses affections neurodégénératives. |
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L'invention concerne des formes modifiées de peptides de conantokine, comprenant fes peptides Con-P modifiés, des acides nucléiques codant pour ceux-ci et des compositions de ceux-ci. L'invention concerne en outre des molécules d'acides nucléiques codant pour des polypeptides de conantokine modifiés chimériques devant être exprimés dans ou sur une membrane d'une cellule cible, des compositions les comprenant et leurs utilisations pour traiter diverses affections neurodégénératives.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210708&DB=EPODOC&CC=WO&NR=2021137245A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210708&DB=EPODOC&CC=WO&NR=2021137245A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BERLIN, Shai</creatorcontrib><creatorcontrib>ZOABI, Shaden</creatorcontrib><creatorcontrib>CARMI, Ido</creatorcontrib><title>CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS</title><description>Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.
L'invention concerne des formes modifiées de peptides de conantokine, comprenant fes peptides Con-P modifiés, des acides nucléiques codant pour ceux-ci et des compositions de ceux-ci. L'invention concerne en outre des molécules d'acides nucléiques codant pour des polypeptides de conantokine modifiés chimériques devant être exprimés dans ou sur une membrane d'une cellule cible, des compositions les comprenant et leurs utilisations pour traiter diverses affections neurodégénératives.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQANNYiPqHBVsDJlGs19uNOUhuJXuHdiHIWYkG4v8xgg-wmmZm5kk04oKmR1Qm8HK1Ds589pZYN-CCqdkaQGNJgZ0Rsu4Eig0DOoKgrOArbllKmMpGKNTov45rCKFlM72k1WUyu_ePMa5-XCTrkr2p0ji8ujgO_S0-47u7SL7Ns6w45Ls9ZsV_1gchyTVY</recordid><startdate>20210708</startdate><enddate>20210708</enddate><creator>BERLIN, Shai</creator><creator>ZOABI, Shaden</creator><creator>CARMI, Ido</creator><scope>EVB</scope></search><sort><creationdate>20210708</creationdate><title>CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS</title><author>BERLIN, Shai ; ZOABI, Shaden ; CARMI, Ido</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2021137245A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BERLIN, Shai</creatorcontrib><creatorcontrib>ZOABI, Shaden</creatorcontrib><creatorcontrib>CARMI, Ido</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BERLIN, Shai</au><au>ZOABI, Shaden</au><au>CARMI, Ido</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS</title><date>2021-07-08</date><risdate>2021</risdate><abstract>Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.
L'invention concerne des formes modifiées de peptides de conantokine, comprenant fes peptides Con-P modifiés, des acides nucléiques codant pour ceux-ci et des compositions de ceux-ci. L'invention concerne en outre des molécules d'acides nucléiques codant pour des polypeptides de conantokine modifiés chimériques devant être exprimés dans ou sur une membrane d'une cellule cible, des compositions les comprenant et leurs utilisations pour traiter diverses affections neurodégénératives.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS |
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