A DRUG CONJUGATE AND APPLICATIONS THEREOF

A linker molecule for targeting molecule-drug conjugate, has the structure of formula (I): A1p-D1q-Y-Lk-W-A2q-D2p (I). A conjugate has the structure of formula (III): A-((compound of formula (I))-PL t) z (III). The conjugate can be used in the manufacture of a medicament for treating a disease. L�...

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Bibliographische Detailangaben
Hauptverfasser:	SHI, Lili, QIN, Gang, LIU, Chong, YUAN, Jinduo, JIANG, Lu, HU, Lehua
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A linker molecule for targeting molecule-drug conjugate, has the structure of formula (I): A1p-D1q-Y-Lk-W-A2q-D2p (I). A conjugate has the structure of formula (III): A-((compound of formula (I))-PL t) z (III). The conjugate can be used in the manufacture of a medicament for treating a disease. L'invention concerne une molécule de liaison pour le ciblage d'un conjugué molécule-médicament, ayant la structure de formule (I) : A1p-D1q-Y-Lk-W-A2q-D2p (I). Le conjugué a la structure de formule (III) : A-((composé de formule (I))-PL t) z (III). Le conjugué peut être utilisé dans la fabrication d'un médicament pour le traitement d'une maladie.