COMPOSITIONS AND METHODS FOR SUBSTITUTED 7-(PIPERAZIN-1-YL)PYRAZOLO[1,5-A]PYRIMIDINE ANALOGS AS INHIBITORS OF KRAS

In one aspect, the disclosure relates to compounds useful as inhibitors of mutant KRAS proteins, methods of making the same, pharmaceutical compositions comprising the same, and methods of treating cancers associated with mutated forms of KRAS using the same. This abstract is intended as a scanning...

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Hauptverfasser: ABEBE, Alemayehu, DILSHA, Kasuni, GILBERTSON, Scott, PAGBA, Cynthia
Format: Patent
Sprache:eng ; fre
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