CRF RECEPTOR ANTAGONISTS AND METHODS OF USE
Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia...
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| creator | KUCERA, David COSTA, Christina Marie HETTINGER, Donald COCHRAN, Brian M LE, Jackie ASHWEEK, Neil J WILLIAMS, John P MELLMER, Max A STIRN, Scott ZEGELMAN, Lev Alexander TUCKER, John Lloyd BRANUM, Shawn |
| description | Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH).
L'invention concerne des composés qui ont un effet antagoniste sur le facteur de libération de la corticotropine (FLC), en particulier le récepteur de FLC 1 (FLC1), ainsi que des préparations, des compositions et des procédés associés pour le traitement de maladies et/ou de troubles qui bénéficieraient de ceux-ci tels que l'hyperplasie surrénale congénitale (HSC). |
| format | Patent |
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L'invention concerne des composés qui ont un effet antagoniste sur le facteur de libération de la corticotropine (FLC), en particulier le récepteur de FLC 1 (FLC1), ainsi que des préparations, des compositions et des procédés associés pour le traitement de maladies et/ou de troubles qui bénéficieraient de ceux-ci tels que l'hyperplasie surrénale congénitale (HSC).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210610&DB=EPODOC&CC=WO&NR=2021113263A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210610&DB=EPODOC&CC=WO&NR=2021113263A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUCERA, David</creatorcontrib><creatorcontrib>COSTA, Christina Marie</creatorcontrib><creatorcontrib>HETTINGER, Donald</creatorcontrib><creatorcontrib>COCHRAN, Brian M</creatorcontrib><creatorcontrib>LE, Jackie</creatorcontrib><creatorcontrib>ASHWEEK, Neil J</creatorcontrib><creatorcontrib>WILLIAMS, John P</creatorcontrib><creatorcontrib>MELLMER, Max A</creatorcontrib><creatorcontrib>STIRN, Scott</creatorcontrib><creatorcontrib>ZEGELMAN, Lev Alexander</creatorcontrib><creatorcontrib>TUCKER, John Lloyd</creatorcontrib><creatorcontrib>BRANUM, Shawn</creatorcontrib><title>CRF RECEPTOR ANTAGONISTS AND METHODS OF USE</title><description>Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH).
L'invention concerne des composés qui ont un effet antagoniste sur le facteur de libération de la corticotropine (FLC), en particulier le récepteur de FLC 1 (FLC1), ainsi que des préparations, des compositions et des procédés associés pour le traitement de maladies et/ou de troubles qui bénéficieraient de ceux-ci tels que l'hyperplasie surrénale congénitale (HSC).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB2DnJTCHJ1dg0I8Q9ScPQLcXT39_MMDgkGsl0UfF1DPPxdghX83RRCg115GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8uL-RgZGhoaGxkZmxo6ExcaoA-MIlnw</recordid><startdate>20210610</startdate><enddate>20210610</enddate><creator>KUCERA, David</creator><creator>COSTA, Christina Marie</creator><creator>HETTINGER, Donald</creator><creator>COCHRAN, Brian M</creator><creator>LE, Jackie</creator><creator>ASHWEEK, Neil J</creator><creator>WILLIAMS, John P</creator><creator>MELLMER, Max A</creator><creator>STIRN, Scott</creator><creator>ZEGELMAN, Lev Alexander</creator><creator>TUCKER, John Lloyd</creator><creator>BRANUM, Shawn</creator><scope>EVB</scope></search><sort><creationdate>20210610</creationdate><title>CRF RECEPTOR ANTAGONISTS AND METHODS OF USE</title><author>KUCERA, David ; COSTA, Christina Marie ; HETTINGER, Donald ; COCHRAN, Brian M ; LE, Jackie ; ASHWEEK, Neil J ; WILLIAMS, John P ; MELLMER, Max A ; STIRN, Scott ; ZEGELMAN, Lev Alexander ; TUCKER, John Lloyd ; BRANUM, Shawn</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2021113263A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KUCERA, David</creatorcontrib><creatorcontrib>COSTA, Christina Marie</creatorcontrib><creatorcontrib>HETTINGER, Donald</creatorcontrib><creatorcontrib>COCHRAN, Brian M</creatorcontrib><creatorcontrib>LE, Jackie</creatorcontrib><creatorcontrib>ASHWEEK, Neil J</creatorcontrib><creatorcontrib>WILLIAMS, John P</creatorcontrib><creatorcontrib>MELLMER, Max A</creatorcontrib><creatorcontrib>STIRN, Scott</creatorcontrib><creatorcontrib>ZEGELMAN, Lev Alexander</creatorcontrib><creatorcontrib>TUCKER, John Lloyd</creatorcontrib><creatorcontrib>BRANUM, Shawn</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUCERA, David</au><au>COSTA, Christina Marie</au><au>HETTINGER, Donald</au><au>COCHRAN, Brian M</au><au>LE, Jackie</au><au>ASHWEEK, Neil J</au><au>WILLIAMS, John P</au><au>MELLMER, Max A</au><au>STIRN, Scott</au><au>ZEGELMAN, Lev Alexander</au><au>TUCKER, John Lloyd</au><au>BRANUM, Shawn</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CRF RECEPTOR ANTAGONISTS AND METHODS OF USE</title><date>2021-06-10</date><risdate>2021</risdate><abstract>Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH).
L'invention concerne des composés qui ont un effet antagoniste sur le facteur de libération de la corticotropine (FLC), en particulier le récepteur de FLC 1 (FLC1), ainsi que des préparations, des compositions et des procédés associés pour le traitement de maladies et/ou de troubles qui bénéficieraient de ceux-ci tels que l'hyperplasie surrénale congénitale (HSC).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE |
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