CRF RECEPTOR ANTAGONISTS AND METHODS OF USE

Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia...

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Bibliographische Detailangaben
Hauptverfasser:	KUCERA, David, COSTA, Christina Marie, HETTINGER, Donald, COCHRAN, Brian M, LE, Jackie, ASHWEEK, Neil J, WILLIAMS, John P, MELLMER, Max A, STIRN, Scott, ZEGELMAN, Lev Alexander, TUCKER, John Lloyd, BRANUM, Shawn
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH). L'invention concerne des composés qui ont un effet antagoniste sur le facteur de libération de la corticotropine (FLC), en particulier le récepteur de FLC 1 (FLC1), ainsi que des préparations, des compositions et des procédés associés pour le traitement de maladies et/ou de troubles qui bénéficieraient de ceux-ci tels que l'hyperplasie surrénale congénitale (HSC).