COMPOSITIONS AND METHODS FOR CULTURING HEMATOPOIETIC STEM AND PROGENITOR CELLS

The present disclosure provides compositions and methods for culturing hematopoietic stem and progenitor cells, while maintaining or increasing the subpopulation of hematopoietic stem cells (HSCs). The methods and compositions describe us a 3D zwitterionic hydrogel to provide a biocompatible culture...

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Bibliographische Detailangaben
Hauptverfasser:	BAI, Tao, CHANDRASEKARAN, Devikha, PRIEVE, Mary, DELANEY, Colleen
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure provides compositions and methods for culturing hematopoietic stem and progenitor cells, while maintaining or increasing the subpopulation of hematopoietic stem cells (HSCs). The methods and compositions describe us a 3D zwitterionic hydrogel to provide a biocompatible culture microenvironment for culturing encapsulated hematopoietic stem and progenitor cells. La présente invention concerne des compositions et des procédés de culture de cellules souches et progénitrices hématopoïétiques, tout en maintenant ou en augmentant la sous-population de cellules souches hématopoïétiques (CSH). Les procédés et les compositions décrivent un hydrogel zwitterionique 3D pour fournir un micro-environnement de culture biocompatible pour la culture de cellules souches et progénitrices hématopoïétiques encapsulées.