A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION

The present invention relates to compounds of formula (1) as shown below having inhibitory activity against KRAS G12D mutation or a salt thereof, and relates to a pharmaceutical composition comprising these compounds as active ingredient. La présente invention concerne un composé ayant une activité...

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Bibliographische Detailangaben
Hauptverfasser:	KAWAI, Yuichi, ASAKURA, Hiroki, SAGARA, Takeshi, HOLVEY, Rhian, SHIBATA, Kazuaki, UNO, Takao, KOBAYAKAWA, Yu, NAKAMURA, Masayuki
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of formula (1) as shown below having inhibitory activity against KRAS G12D mutation or a salt thereof, and relates to a pharmaceutical composition comprising these compounds as active ingredient. La présente invention concerne un composé ayant une activité inhibitrice contre la mutation KRAS G12D ou un sel de celui-ci, et concerne une composition pharmaceutique comprenant ledit composé en tant que principe actif.