SECRETABLE PROTEIN INDUCED IMMUNE TOLERIZATION AND TREATMENT OF AUTOIMMUNE, ALLERGIC AND OTHER DISEASES AND DISORDERS
Nucleic acids encoding fusion proteins that contain an unwanted antigen and a leader sequence for cell secretion are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat autoimmune, all...
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| creator | QUINN, William MINGOZZI, Federico ANDERSON, David William GURDA, Brittney L YAZICIOGLU, Mustafa N |
| description | Nucleic acids encoding fusion proteins that contain an unwanted antigen and a leader sequence for cell secretion are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat autoimmune, allergic and other diseases and disorders, such as multiple sclerosis.
L'invention concerne des acides nucléiques codant pour des protéines hybrides qui contiennent un antigène indésirable et une séquence de tête pour la sécrétion cellulaire. L'invention concerne également des cassettes d'expression, des vecteurs, des cellules et des lignées cellulaires contenant les acides nucléiques, ainsi que des procédés d'utilisation des acides nucléiques pour traiter des maladies et des troubles auto-immuns, allergiques et autres, tels que la sclérose en plaques. |
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L'invention concerne des acides nucléiques codant pour des protéines hybrides qui contiennent un antigène indésirable et une séquence de tête pour la sécrétion cellulaire. L'invention concerne également des cassettes d'expression, des vecteurs, des cellules et des lignées cellulaires contenant les acides nucléiques, ainsi que des procédés d'utilisation des acides nucléiques pour traiter des maladies et des troubles auto-immuns, allergiques et autres, tels que la sclérose en plaques.</description><language>eng ; fre</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SUGARS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210527&DB=EPODOC&CC=WO&NR=2021102182A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210527&DB=EPODOC&CC=WO&NR=2021102182A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>QUINN, William</creatorcontrib><creatorcontrib>MINGOZZI, Federico</creatorcontrib><creatorcontrib>ANDERSON, David William</creatorcontrib><creatorcontrib>GURDA, Brittney L</creatorcontrib><creatorcontrib>YAZICIOGLU, Mustafa N</creatorcontrib><title>SECRETABLE PROTEIN INDUCED IMMUNE TOLERIZATION AND TREATMENT OF AUTOIMMUNE, ALLERGIC AND OTHER DISEASES AND DISORDERS</title><description>Nucleic acids encoding fusion proteins that contain an unwanted antigen and a leader sequence for cell secretion are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat autoimmune, allergic and other diseases and disorders, such as multiple sclerosis.
L'invention concerne des acides nucléiques codant pour des protéines hybrides qui contiennent un antigène indésirable et une séquence de tête pour la sécrétion cellulaire. L'invention concerne également des cassettes d'expression, des vecteurs, des cellules et des lignées cellulaires contenant les acides nucléiques, ainsi que des procédés d'utilisation des acides nucléiques pour traiter des maladies et des troubles auto-immuns, allergiques et autres, tels que la sclérose en plaques.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwkAQBNA0FqL-w4KtgomN7Xq3MQfJrextCNiEIGclGoj-vyH6ARbDMMObJ-9ARkjxWBKchZWcB-dtbciCq6raEyiXJO6C6tgDegsqhFqRV-AcsFb-wg1gOcqTM5NiLUjAukAYKEzXOFgsSVgms1t3H-Lq14tknZOaYhv7ZxuHvrvGR3y1DWe7LE3HHDJM9_-pD-UqOg8</recordid><startdate>20210527</startdate><enddate>20210527</enddate><creator>QUINN, William</creator><creator>MINGOZZI, Federico</creator><creator>ANDERSON, David William</creator><creator>GURDA, Brittney L</creator><creator>YAZICIOGLU, Mustafa N</creator><scope>EVB</scope></search><sort><creationdate>20210527</creationdate><title>SECRETABLE PROTEIN INDUCED IMMUNE TOLERIZATION AND TREATMENT OF AUTOIMMUNE, ALLERGIC AND OTHER DISEASES AND DISORDERS</title><author>QUINN, William ; MINGOZZI, Federico ; ANDERSON, David William ; GURDA, Brittney L ; YAZICIOGLU, Mustafa N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2021102182A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>QUINN, William</creatorcontrib><creatorcontrib>MINGOZZI, Federico</creatorcontrib><creatorcontrib>ANDERSON, David William</creatorcontrib><creatorcontrib>GURDA, Brittney L</creatorcontrib><creatorcontrib>YAZICIOGLU, Mustafa N</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>QUINN, William</au><au>MINGOZZI, Federico</au><au>ANDERSON, David William</au><au>GURDA, Brittney L</au><au>YAZICIOGLU, Mustafa N</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SECRETABLE PROTEIN INDUCED IMMUNE TOLERIZATION AND TREATMENT OF AUTOIMMUNE, ALLERGIC AND OTHER DISEASES AND DISORDERS</title><date>2021-05-27</date><risdate>2021</risdate><abstract>Nucleic acids encoding fusion proteins that contain an unwanted antigen and a leader sequence for cell secretion are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat autoimmune, allergic and other diseases and disorders, such as multiple sclerosis.
L'invention concerne des acides nucléiques codant pour des protéines hybrides qui contiennent un antigène indésirable et une séquence de tête pour la sécrétion cellulaire. L'invention concerne également des cassettes d'expression, des vecteurs, des cellules et des lignées cellulaires contenant les acides nucléiques, ainsi que des procédés d'utilisation des acides nucléiques pour traiter des maladies et des troubles auto-immuns, allergiques et autres, tels que la sclérose en plaques.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS |
| title | SECRETABLE PROTEIN INDUCED IMMUNE TOLERIZATION AND TREATMENT OF AUTOIMMUNE, ALLERGIC AND OTHER DISEASES AND DISORDERS |
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