SUBSTITUTED IMIDAZO PYRIMIDINE EP3 ANTAGONISTS

The invention relates to substituted imidazo pyrimidine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and...

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Bibliographische Detailangaben
Hauptverfasser:	FOLLMANN, Markus, MÜLLER, Steffen, POOK, Elisabeth, CANDISH, Lisa, GAUGAZ, Fabienne, GERDES, Christoph, BUCHMÜLLER, Anja, SÜSSMEIER, Frank, SCHOHE-LOOP, Rudolf, LANG, Dieter
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to substituted imidazo pyrimidine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders. These compounds are EP3 antagonists. L'invention concerne des dérivés d'imidazo pyrimidine substitués et des procédés pour leur préparation, ainsi que leur utilisation pour la préparation de médicaments pour le traitement et/ou la prophylaxie de maladies, en particulier de troubles cardiovasculaires, de préférence de troubles thrombotiques ou thromboemboliques, et du diabète, ainsi que de troubles urogénitaux et ophtalmiques. Ces composés sont des antagonistes EP3.