COMPOUNDS FOR THE IDENTIFICATION OF MICROBIAL CLASSES AND USES THEREOF
Described herein are compounds based on the formula X-L-R, wherein X is a recognition element that binds to at least one, but not all three, of a Gram-positive microbe population, a Gram-negative microbe population, and a fungal population, L is a bond or a linker, and R is a reporter or an antibody...
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Zusammenfassung: | Described herein are compounds based on the formula X-L-R, wherein X is a recognition element that binds to at least one, but not all three, of a Gram-positive microbe population, a Gram-negative microbe population, and a fungal population, L is a bond or a linker, and R is a reporter or an antibody ligand. These compounds are useful as, among other things, diagnostic agents for identifying a disease state in a subject or identifying a contaminant in or on a sample. Also described herein are compositions containing such compounds and methods of using the compounds and compositions.
L'invention concerne des composés de formule (I), (Ia), et (II)-(IV) qui sont utiles, entre autres, comme agents de diagnostic pour identifier un état pathologique chez un sujet ou identifier un contaminant dans ou sur un échantillon. L'invention concerne également des compositions comprenant ces composés et des méthodes d'utilisation de ces composés et compositions. |
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