COMPOSITION FOR AUGMENTING STEMNESS AND USE THEREOF

The present application pertains to a sialyloligosaccharide for augmenting the stemness of stem cells and a use thereof and provides a composition for augmenting stemness of stem cells, a method for culturing stem cells in a medium containing a sialyloligosaccharide, a method for augmenting stemness...

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Bibliographische Detailangaben
Hauptverfasser:	WOO, Jin Suk, BAEK, Ah Reum, CHO, Sung Rae, KIM, Sung Hoon, KIM, Dae Hee, KIM, Li La
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present application pertains to a sialyloligosaccharide for augmenting the stemness of stem cells and a use thereof and provides a composition for augmenting stemness of stem cells, a method for culturing stem cells in a medium containing a sialyloligosaccharide, a method for augmenting stemness of stem cells, a stem cell with augmented stemness, obtained by the method, and a cell therapy composition comprising the stem cells as an active ingredient. The composition or the method according to an aspect can suppress the aging of stem cells and can maintain and augment stemness. La présente invention concerne un sialylooligosaccharide permettant d'augmenter le caractère souche de cellules souches et une utilisation de ce dernier, et fournit une composition pour augmenter le caractère souche de cellules souches, un procédé de culture de cellules souches dans un milieu contenant un sialylooligosaccharide, un procédé d'augmentation du caractère souche de cellules souches, une cellule souche présentant un caractère souche augmenté, obtenu par le procédé, et une composition de thérapie cellulaire comprenant les cellules souches en tant que principe actif. La composition ou le procédé selon un aspect peut supprimer le vieillissement de cellules souches et peut maintenir et augmenter le caractère souche. 본 출원은 줄기세포의 줄기세포능을 증대시키는 시알릴올리고당 및 이의 용도에 관한 것으로서, 줄기세포의 줄기세포능을 증대시키기 위한 조성물, 시알릴올리고당을 포함하는 배지에서 줄기세포를 배양하는 방법, 줄기세포의 줄기세포능을 증대시키는 방법, 상기 방법을 통해 수득한 줄기세포능이 증대된 줄기세포, 및 상기 줄기세포를 유효성분으로 포함하는 세포 치료용 조성물 등을 제공한다. 일 양상에 따른 조성물 또는 방법에 의하면, 줄기세포의 노화 억제되고, 줄기세포능을 유지하고 증대시킬 수 있다.