BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE

Described herein are bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins. L'invention concerne des composés de dégradatio...

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Hauptverfasser:	ARISTA, Luca, DOUMAMPOUOM-METOUL, Lionel, LORBER, Julien, JEULIN, Ingrid Karen Jennifer, HEBACH, Christina, YAMADA, Ken, GOUDE, Marie-Line, ZOLLER, Thomas, D'ALESSANDRO, Pier Luca, MA, Fupeng, VULPETTI, Anna, BROENNIMANN, Valerie, KIRMAN, Louise Clare, HOLLINGWORTH, Gregory John
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Described herein are bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins. L'invention concerne des composés de dégradation bifonctionnels, leurs diverses cibles, leur préparation, des compositions pharmaceutiques les comprenant et leur utilisation dans le traitement d'affections, de maladies et de troubles médiés par diverses protéines cibles.