CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES

Disclosed are antibody-drug conjugates and compositions thereof for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof. L'invention concerne des conjugués anticorps-médicament et des compositions de ceux-ci pour l&#...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	PADMANABHAN, Seetharamaiyer, GIMI, Rayomand H, CLEARY, Dillon, SHERI, Anjaneyulu, SCHMIDT, Diane, IYER, Radhakrishnan P, BASKARAN, Subramanian
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!