4-1BB AND OX40 BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS, ANTIBODIES AGAINST 4-1BB, ANTIBODIES AGAINST OX40

The present disclosure provides antibodies that specifically bind to 4-1BB and/or OX40, including bispecific antibodies that bind to 4-1BB and OX40, and compositions comprising such antibodies. Also provided are methods for treating disorders, such as cancer, using such antibodies and compositions....

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Bibliographische Detailangaben
Hauptverfasser: PAVLIK, Peter, MISHER, Lynda, BIENVENUE, David Leonard, HERNANDEZ-HOYOS, Gabriela, MITCHELL, Danielle Marie, NELSON, Michelle Hase
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present disclosure provides antibodies that specifically bind to 4-1BB and/or OX40, including bispecific antibodies that bind to 4-1BB and OX40, and compositions comprising such antibodies. Also provided are methods for treating disorders, such as cancer, using such antibodies and compositions. La présente invention concerne des anticorps qui se lient spécifiquement à 4-1BB et/ou OX40, comprenant des anticorps bispécifiques qui se lient à 4-1BB et OX40, et des compositions comprenant de tels anticorps. L'invention concerne également des méthodes de traitement de troubles, tels que le cancer, à l'aide de tels anticorps et de telles compositions.