INFLAMMATORY BOWEL DISEASES THERAPY INVOLVING DISRUPTING CCR9:DRD5 HETEROMER ASSEMBLY

A method for disrupting the formation of CCR9:DRD5 heteromer assembly in a subject involving administering to the subject a pharmaceutical composition having at least on disrupter agent that inhibits or blocks the interaction between CCR9 and DRD5. Also, peptides and peptide analogs for use as the d...

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Hauptverfasser:	CAMPOS ACUÑA, Javier, FRANCO FERNÁNDEZ, Rafael, OSORIO BARRIOS, Francisco, PACHECO RIVERA, Rodrigo A, NAVARRO BRUGAL, Gemma
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A method for disrupting the formation of CCR9:DRD5 heteromer assembly in a subject involving administering to the subject a pharmaceutical composition having at least on disrupter agent that inhibits or blocks the interaction between CCR9 and DRD5. Also, peptides and peptide analogs for use as the disrupter agent and pharmaceutical compositions containing the peptides and peptide analogs. L'invention concerne un procédé destiné à perturber la formation de l'assemblage hétéromère CCR9:DRD5 chez un sujet, comprenant l'administration au sujet d'une composition pharmaceutique ayant au moins un agent perturbateur qui inhibe ou bloque l'interaction entre CCR9 et DRD5. L'invention concerne également des peptides et des analogues peptidiques destinés à être utilisés en tant qu'agent perturbateur et des compositions pharmaceutiques contenant les peptides et les analogues peptidiques.