TREATMENT OF DISEASES BY EXPRESSION OF AN ENZYME WHICH HAS A DEOXYRIBONUCLEASE (DNASE) ACTIVITY

The invention relates to the delivery and/or expression of an enzyme which has a deoxyribonuclease (DNase) activity to liver, nervous system and/or intestine resulting in enhanced clearance of cell free DNA (cfDNA) useful for treatment of various diseases and conditions, including cancer and neurode...

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Bibliographische Detailangaben
Hauptverfasser:	GENKIN, Dmitry Dmitrievich, TETS, Georgy Viktorovich, TETS, Viktor Veniaminovich
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the delivery and/or expression of an enzyme which has a deoxyribonuclease (DNase) activity to liver, nervous system and/or intestine resulting in enhanced clearance of cell free DNA (cfDNA) useful for treatment of various diseases and conditions, including cancer and neurodegeneration. L'invention concerne l'administration et/ou l'expression d'une enzyme qui a une activité désoxyribonucléase (DNase) spécifique du foie, du système nerveux et/ou de l'intestin, ce qui permet d'améliorer la libération d'ADN acellulaire (cfDNA) utile pour le traitement de diverses maladies et affections, y compris le cancer et la neurodégénérescence.