PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS

The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer. La présente invention concerne des conjugués peptidiques d'agents de ciblage de microtubules tels que des dérivés d...

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Bibliographische Detailangaben
Hauptverfasser:	VOLKMANN, Robert A, CSENGERY, Johanna Marie, MAGUIRE, Robert John, MARSHALL, Daniel Richard
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer. La présente invention concerne des conjugués peptidiques d'agents de ciblage de microtubules tels que des dérivés de maytansinoïdes qui sont utiles pour le traitement de maladies telles que le cancer.