RECOMBINANT VECTOR FOR PRODUCING ANTIBODY FOR TREATING CANINE PARVOVIRUS INFECTION, AND USE OF SAME

The present invention relates to: a recombinant vector for expressing single-chain variable fragment 8 (scFv8) in plants, scFv8 being a recombinant antibody exhibiting the ability to neutralize canine parvovirus (CPV); a transformant transformed by the recombinant vector; the ScFv8 antibody isolated...

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Hauptverfasser: SOHN, Eun-Ju, KANG, Hyang Ju, LEE, Sangmin, PARK, Youngmin
Format: Patent
Sprache:eng ; fre ; kor
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Zusammenfassung:The present invention relates to: a recombinant vector for expressing single-chain variable fragment 8 (scFv8) in plants, scFv8 being a recombinant antibody exhibiting the ability to neutralize canine parvovirus (CPV); a transformant transformed by the recombinant vector; the ScFv8 antibody isolated from the transformant; and a composition which is for preventing or treating canine parvovirus infection and comprises the scFv8 antibody as an active ingredient. La présente invention concerne : un vecteur recombinant pour l'expression d'un fragment variable à chaîne unique 8 (scFv8) dans les plantes, le scFv8 étant un anticorps recombinant présentant la capacité de neutraliser le parvovirus canin (CPV); un transformant transformé par le vecteur recombinant; l'anticorps scfv8 isolé à partir du transformant; et une composition qui est destinée à prévenir ou à traiter une infection par le parvovirus canin et qui comprend l'anticorps scFv8 en tant que principe actif. 본 발명은 개 파보바이러스(Canine parvovirus, CPV)에 대한 중화능을 보이는 재조합 항체 scFv8(single-chain variable fragment 8)을 식물체에서 발현시키기 위한 재조합 벡터, 상기 재조합 벡터에 의해 형질전환된 형질전환체, 상기 형질전환체에서 분리된 scFv8 항체 및 이를 유효성분으로 포함하는 개 파보바이러스 감염증에 대한 예방 또는 치료용 조성물 등에 관한 것이다.