2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS
Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and...
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| creator | FOURNIER, Jeremy Thomas Andre LELETI, Manmohan Reddy DREW, Samuel Lawrie THOMAS-TRAN, Rhiannon MILES, Dillon Harding MATA, Guillaume JEFFREY, Jenna Leigh LAWSON, Kenneth Victor POWERS, Jay Patrick YAN, Xuelei BEATTY, Joel Worley SHARIF, Ehesan Ul MAILYAN, Artur Karenovich |
| description | Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3Kγ.
L'invention concerne des composés qui inhibent PI3Kγ, et des compositions contenant ces composés et des procédés de synthèse desdits composés. L'invention concerne également l'utilisation de tels composés et de telles compositions pour le traitement d'un réseau divers de maladies, de troubles et d'états, y compris des troubles liés au cancer et au système immunitaire qui sont médiés, au moins en partie, par PI3Kγ. |
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L'invention concerne des composés qui inhibent PI3Kγ, et des compositions contenant ces composés et des procédés de synthèse desdits composés. L'invention concerne également l'utilisation de tels composés et de telles compositions pour le traitement d'un réseau divers de maladies, de troubles et d'états, y compris des troubles liés au cancer et au système immunitaire qui sont médiés, au moins en partie, par PI3Kγ.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201210&DB=EPODOC&CC=WO&NR=2020247496A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201210&DB=EPODOC&CC=WO&NR=2020247496A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FOURNIER, Jeremy Thomas Andre</creatorcontrib><creatorcontrib>LELETI, Manmohan Reddy</creatorcontrib><creatorcontrib>DREW, Samuel Lawrie</creatorcontrib><creatorcontrib>THOMAS-TRAN, Rhiannon</creatorcontrib><creatorcontrib>MILES, Dillon Harding</creatorcontrib><creatorcontrib>MATA, Guillaume</creatorcontrib><creatorcontrib>JEFFREY, Jenna Leigh</creatorcontrib><creatorcontrib>LAWSON, Kenneth Victor</creatorcontrib><creatorcontrib>POWERS, Jay Patrick</creatorcontrib><creatorcontrib>YAN, Xuelei</creatorcontrib><creatorcontrib>BEATTY, Joel Worley</creatorcontrib><creatorcontrib>SHARIF, Ehesan Ul</creatorcontrib><creatorcontrib>MAILYAN, Artur Karenovich</creatorcontrib><title>2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS</title><description>Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3Kγ.
L'invention concerne des composés qui inhibent PI3Kγ, et des compositions contenant ces composés et des procédés de synthèse desdits composés. L'invention concerne également l'utilisation de tels composés et de telles compositions pour le traitement d'un réseau divers de maladies, de troubles et d'états, y compris des troubles liés au cancer et au système immunitaire qui sont médiés, au moins en partie, par PI3Kγ.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAw0jHWMdUNCfIMDnUKDvEMCQ1xdVEIiAxyjPL38Y82BMo5xgK5nr6eLp5-rgrO_r4B_qF-LsE8DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IAAhNzE0szRwNjYlTBQAbNCmv</recordid><startdate>20201210</startdate><enddate>20201210</enddate><creator>FOURNIER, Jeremy Thomas Andre</creator><creator>LELETI, Manmohan Reddy</creator><creator>DREW, Samuel Lawrie</creator><creator>THOMAS-TRAN, Rhiannon</creator><creator>MILES, Dillon Harding</creator><creator>MATA, Guillaume</creator><creator>JEFFREY, Jenna Leigh</creator><creator>LAWSON, Kenneth Victor</creator><creator>POWERS, Jay Patrick</creator><creator>YAN, Xuelei</creator><creator>BEATTY, Joel Worley</creator><creator>SHARIF, Ehesan Ul</creator><creator>MAILYAN, Artur Karenovich</creator><scope>EVB</scope></search><sort><creationdate>20201210</creationdate><title>2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS</title><author>FOURNIER, Jeremy Thomas Andre ; LELETI, Manmohan Reddy ; DREW, Samuel Lawrie ; THOMAS-TRAN, Rhiannon ; MILES, Dillon Harding ; MATA, Guillaume ; JEFFREY, Jenna Leigh ; LAWSON, Kenneth Victor ; POWERS, Jay Patrick ; YAN, Xuelei ; BEATTY, Joel Worley ; SHARIF, Ehesan Ul ; MAILYAN, Artur Karenovich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020247496A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>FOURNIER, Jeremy Thomas Andre</creatorcontrib><creatorcontrib>LELETI, Manmohan Reddy</creatorcontrib><creatorcontrib>DREW, Samuel Lawrie</creatorcontrib><creatorcontrib>THOMAS-TRAN, Rhiannon</creatorcontrib><creatorcontrib>MILES, Dillon Harding</creatorcontrib><creatorcontrib>MATA, Guillaume</creatorcontrib><creatorcontrib>JEFFREY, Jenna Leigh</creatorcontrib><creatorcontrib>LAWSON, Kenneth Victor</creatorcontrib><creatorcontrib>POWERS, Jay Patrick</creatorcontrib><creatorcontrib>YAN, Xuelei</creatorcontrib><creatorcontrib>BEATTY, Joel Worley</creatorcontrib><creatorcontrib>SHARIF, Ehesan Ul</creatorcontrib><creatorcontrib>MAILYAN, Artur Karenovich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FOURNIER, Jeremy Thomas Andre</au><au>LELETI, Manmohan Reddy</au><au>DREW, Samuel Lawrie</au><au>THOMAS-TRAN, Rhiannon</au><au>MILES, Dillon Harding</au><au>MATA, Guillaume</au><au>JEFFREY, Jenna Leigh</au><au>LAWSON, Kenneth Victor</au><au>POWERS, Jay Patrick</au><au>YAN, Xuelei</au><au>BEATTY, Joel Worley</au><au>SHARIF, Ehesan Ul</au><au>MAILYAN, Artur Karenovich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS</title><date>2020-12-10</date><risdate>2020</risdate><abstract>Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3Kγ.
L'invention concerne des composés qui inhibent PI3Kγ, et des compositions contenant ces composés et des procédés de synthèse desdits composés. L'invention concerne également l'utilisation de tels composés et de telles compositions pour le traitement d'un réseau divers de maladies, de troubles et d'états, y compris des troubles liés au cancer et au système immunitaire qui sont médiés, au moins en partie, par PI3Kγ.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | 2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS |
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