2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS

Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	FOURNIER, Jeremy Thomas Andre, LELETI, Manmohan Reddy, DREW, Samuel Lawrie, THOMAS-TRAN, Rhiannon, MILES, Dillon Harding, MATA, Guillaume, JEFFREY, Jenna Leigh, LAWSON, Kenneth Victor, POWERS, Jay Patrick, YAN, Xuelei, BEATTY, Joel Worley, SHARIF, Ehesan Ul, MAILYAN, Artur Karenovich
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3Kγ. L'invention concerne des composés qui inhibent PI3Kγ, et des compositions contenant ces composés et des procédés de synthèse desdits composés. L'invention concerne également l'utilisation de tels composés et de telles compositions pour le traitement d'un réseau divers de maladies, de troubles et d'états, y compris des troubles liés au cancer et au système immunitaire qui sont médiés, au moins en partie, par PI3Kγ.