COMPOSITIONS AND METHODS FOR TREATMENT OF HEMOCHROMATOSIS

This application provides polynucleotides comprising a coding sequence for a functionally active hereditary hemochromatosis protein (HFE) or a functionally active fragment thereof. The invention further provides compositions comprising said polynucleotides and their use in methods of preventing or t...

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Bibliographische Detailangaben
Hauptverfasser:	CATALDO, Jason Robert, DAUGHERTY, Sean Christopher, CARSON, Rosaline Do, WONG, Timothy Preston
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	This application provides polynucleotides comprising a coding sequence for a functionally active hereditary hemochromatosis protein (HFE) or a functionally active fragment thereof. The invention further provides compositions comprising said polynucleotides and their use in methods of preventing or treating hemochromatosis in a subject. L'invention concerne des polynucléotides comprenant une séquence de codage pour une protéine fonctionnellement active de l'hémochromatose héréditaire (HFE) ou un fragment fonctionnellement actif de celle-ci. L'invention concerne en outre des compositions comprenant lesdits polynucléotides et leur utilisation dans des procédés de prévention ou de traitement de l'hémochromatose chez un sujet.